Fuse-It-siRNA for siRNA Transfection

A fusion reagent for rapid and efficient gene silencing in living cells—the improvement of siRNA transfection

• Exceptionally efficient siRNA transfection, especially in primary and non-dividing cells, such as keratinocytes
• Extremely low cytotoxicity
• Fastest siRNA delivery—no endocytosis or lysosomal degradation

Applications

• Gene silencing / protein knockdown
• RNA interference (RNAi)
• Regulation of gene expression by siRNA transfection

Technical Features

• Lipofection-independent transfer of siRNA into living cells
• Fast siRNA transfection into the cytoplasm: no endocytosis, no lysosomal degradation, and no gene transfer to the nucleus
• siRNA transfer completed within 5-20 minutes
• Small amount of siRNA is sufficient for effective knockdown
• Excellent biocompatibility because of low cytotoxicity
• siRNA transfer into cells without generating genetically modified organisms (GMO), in contrast to viral or plasmid-based approaches

Specifications