PET Version Array: Polyethylene terephthalate, standard thickness 0.25mm
Each of the 96 wells in a standard plate configuration contains two circular 350 μm diameter active electrodes on a transparent PET substrate (measuring from 100-200 cells). As with other 1E arrays, a major use of this array is for the ECIS wound-healing assays where the small electrodes assures the high current pulse will result in complete cell killing.
Only a small population of cells is monitored on the small electrodes resulting in a fluctuating impedance signal due to the random like movement of the cells (micromotion).
Applications include:
• Cell Migration
• Measurement of micromotion
• Cell-ECM protein interactions
• Signal transduction assays
• Detection of invasion of endothelial cell layers by metastatic cells
• Barrier function
• In situ Cell Electroporation and Monitoring